Disease Alzheimer s And Parkinson s Disease Essay

Abstract: Neurodegenerative diseases are progressive disorders that mainly affect neuronal cells and functions, and commonly characterized by abnormal protein metabolism and aggregations i.e. Alzheimer’s disease (AD), Parkinson’s disease (PD), Huntington’s disease, Prion diseases, Motor neurone disease, Amyotrophic lateral sclerosis (ALS), Lou Gehrig’s disease, among others. Currently, there is no single cure out there to treat these debilitating diseases. However, present therapies available either slow down the disease progression or inhibit mutant protein’s aggregation. Recent studies are facilitating our understandings in both neurochemistry and the genetic pathogenesis of the disease nature, which may result in exciting new discoveries and also provide a platform for the development of new effective drugs to cure these devastating diseases. This essay will discuss the shared pathological characteristics for common therapeutic approaches to combat agains t these incapacitating diseases with particular focus on the two most common neurodegenerative diseases: Alzheimer’s and Parkinson’s disease. Introduction: Neurodegenerative diseases are characterised by progressive loss of structure and, or function of particular groups of neurons (Gorman, 2008). The share common pathological features found in all neurodegenerative diseases are - deposits of misfolded protein aggregates (I.e. microscopically visible inclusions or plaques) and neurotoxic protein accumulations inShow MoreRelatedThe Common Types Of Dementia1013 Words   |  5 PagesIt’s a progressive disease which means it gets worse over time. If diagnosed early on, the quality of life for people with dementia as well as their family members can be significantly improved. There are many different types of dementias although some are far more reciprocal than others. 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